Meet
Elizabet Shvets

Consultant II

Elizabet Shvets supports clients in commercializing cell and gene therapies (CGTs) by providing guidance on coding, coverage, and reimbursement approaches.

She also leverages insights from claims-based analyses to support clients in assessing reimbursement rates, target patient demographics, patient location relative to treatment sites, and overall costs throughout CGT journey. Claims-based projects include NTAP, cost-to-charge ratio, patient journey, and treatment network analyses. Elizabet also provides guidance on the unique operational, financial, competitive, and distribution considerations associated with cell and gene therapies and helps clients consider how these elements can impact launch. Elizabet also provided end-to-end support for a gene therapy manufacturer for several years, throughout her time at Avalere until expected launch. This included assessing competitor dynamics and scenario planning, value message building, reimbursement and coding roadmap development, coverage assessment, and development of strategic recommendations for executive level stakeholders.

Prior to joining Avalere, Elizabet worked as a research assistant at the Hunter College Economics Department where she conducted empirical and descriptive research to support health economics research, including the impact of vertical integration on medical malpractice. Additionally, she completed an internship in the Policy and Research Department at PhRMA where she analyzed the drug policy landscape and conducted research to support advocacy efforts around cell and gene therapies and the 340B program. Elizabet is a PhD Candidate in health policy at the George Washington University. She also received a BA and MA in economics from Hunter College and minored in mathematics.

Authored Content


The inpatient rule proposes a 17% increase for CAR-T stays and several CGTs are under review for New Technology Add-on Payments.

Medicare CAR-T payment remains stable; CMS proposed structural changes for New Technology Add-on Payments (NTAP).

Specialty pharmacies are evolving to support the unique distribution requirements of CGTs and the complex patient journey from diagnosis to treatment.

In this installment of our 2024 Trends Influencing Rare Disease series, Avalere experts summarize key learnings for pharmaceutical companies to consider.

Medicare CAR-T payment remains stable, but changes to outlier payments and NTAP eligibility may create challenges.

Policy proposals for Medicare’s CAR-T inpatient reimbursement reflect additional cases and increase clinical trial payment.

In 2022, over half of payers had at least one outcomes-based contract (OBC) and used claims-based outcomes, despite acknowledging the limitations of using claims to measure clinical benefit.

Starting July 1, manufacturers can report multiple best prices for some value-based arrangements, which may encourage broader use of innovative contracting.

Join Avalere’s panel of market access and policy experts for a discussion on the growing cell and gene therapy (CGT) pipeline, an in-depth look at the unique opportunities and challenges these novel therapies present, and an overview of the many hurdles stakeholders need to navigate for success.

In September 2021, Avalere conducted an online survey of 51 US-based health plans and pharmacy benefit managers (PBMs), representing roughly 59 million covered lives. The survey indicates that 56% of payers have executed an outcomes-based contract (OBC) as of September 2021.

The intersection of upcoming changes to drug pricing metrics will require new methods of calculating and reporting government pricing with implications for net pricing and contracting strategies.

Manufacturers currently in the developmental phase for drug assets targeting rare or orphan diseases should assess the commercialization implications when bringing novel therapies to market and how they may differ from the standard pharmaceutical supply chain and economics.